Exendin(9-39) amide
CAS No. : 133514-43-9
(Synonyms: Avexitide)
| Size | Price | Stock |
|---|---|---|
| 500μg | $204 | Get quote |
| 1mg | $324 | In-stock |
| 5mg | $640 | In-stock |
| 10mg | $905 | In-stock |
| 25mg | $1360 | In-stock |
| 50mg | $1840 | In-stock |
| 100mg | $2400 | In-stock |
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| Cat. No. : | HY-P0264 |
| M.Wt: | 3369.76 |
| Formula: | C149H234N40O47S |
| Purity: | >98 % |
| Solubility: | H2O : 50 mg/mL (ultrasonic) |
Exendin(9-39) amide (Avexitide) is a glucagon-like peptide-1 (GLP-1) antagonist that competes with endogenous GLP-1 for binding to GLP-1 receptors, thereby antagonizing the effects of excess GLP-1 secretion. Exendin(9-39) amide can be used to study postoperative hypoglycemia (PBH)[1]. In Vitro: GLP-1 plays a role in the control of fasting glucose. Avexitide (Exendin (9-39)), a truncated form of the GLP-1 agonist exendin-4, is a specific GLP-1 receptor antagonist[1]. In Vivo: Continuous subcutaneous infusion of Avexitide (Exendin (9-39)) significantly raises fasting blood glucose levels in SUR-1 -/- mice without affecting glucose tolerance[2].
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