PF-5190457
CAS No. : 1334782-79-4
(Synonyms: PF-05190457)
| Size | Price | Stock |
|---|---|---|
| 5mg | $90 | In-stock |
| 10mg | $160 | In-stock |
| 25mg | $350 | In-stock |
| 50mg | $510 | In-stock |
| 100mg | $936 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-12584 |
| M.Wt: | 512.67 |
| Formula: | C29H32N6OS |
| Purity: | >98 % |
| Solubility: | DMSO : 250 mg/mL (ultrasonic);Ethanol : 100 mg/mL (ultrasonic) |
PF-5190457 (PF-05190457) is a potent and selective ghrelin receptor inverse agonist with a pKi of 8.36[1]. IC50 & Target: pKi: 8.36 (Humnan ghrelin receptor)[1] In Vitro: PF-5190457 has a superior balance of ghrelin receptor pharmacology and off-target selectivity[1]. In Vivo: PF-5190457 has excellent selectivity and demonstrates robust increases in glucose-stimulated insulin secretion in human whole and dispersed islets[1].
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