(±)-ML 209
CAS No. : 1334526-14-5
| Size | Price | Stock |
|---|---|---|
| 1mg | $114 | In-stock |
| 5mg | $270 | In-stock |
| 10mg | $350 | In-stock |
| 25mg | $571 | In-stock |
| 50mg | $830 | In-stock |
| 100mg | $1140 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-126037 |
| M.Wt: | 441.52 |
| Formula: | C25H31NO6 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
(±)-ML 209 (compound 4n), a diphenylpropanamide, is a retinoic acid-related orphan receptor RORγ antagonist with an IC50 of 1.1 μM. (±)-ML 209 inhibits RORγt transcriptional activity with an IC50 of 300 nM in HEK293t cells. (±)-ML 209 inhibits the transcriptional activity of RORγt, but not RORα in cells. (±)-ML 209 selectively inhibits murine Th17 cell differentiation without affecting the differentiation of naïve CD4+ T cells into other lineages, including Th1 and regulatory T cells[1].
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