Itacitinib
CAS No. : 1334298-90-6
(Synonyms: INCB039110)
| Size | Price | Stock |
|---|---|---|
| 1mg | $50 | In-stock |
| 5mg | $140 | In-stock |
| 10mg | $230 | In-stock |
| 25mg | $420 | In-stock |
| 50mg | $690 | In-stock |
| 100mg | $1100 | In-stock |
| 500mg | $2200 | In-stock |
| 1 g | Get quote | |
| 5 g | Get quote | |
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| Cat. No. : | HY-16997 |
| M.Wt: | 553.51 |
| Formula: | C26H23F4N9O |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 30 mg/mL |
Itacitinib (INCB039110) is an orally active and selective inhibitor of JAK1 with an IC50 of 2 nM for human JAK1. Itacitinib shows >20-fold selectivity for JAK1 over JAK2 and >100-fold over JAK3 and TYK2; Itacitinib is used in the research of myelofibrosis[1][2]. IC50 & Target: JAK[1] In Vitro: Itacitinib (INCB039110) is a potent and selective inhibitor of JAK1, with >20-fold selectivity for JAK1 over JAK2 and >100-fold over JAK3 and TYK2. Itacitinib is used in the research of myelofibrosis[1].
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