MG-115
CAS No. : 133407-86-0
| Size | Price | Stock |
|---|---|---|
| 1mg | $56 | In-stock |
| 5mg | $125 | In-stock |
| 10mg | $220 | In-stock |
| 25mg | $462 | In-stock |
| 50mg | $690 | In-stock |
| 100mg | $1039 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-108552 |
| M.Wt: | 461.59 |
| Formula: | C25H39N3O5 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C) |
MG-115 is a potent and reversible proteasome inhibitor, with Kis of 21 nM and 35 nM for 20S and 26S proteasome, respectively. MG-115 specifically inhibit the chymotrypsin-like activity of the proteasome, induces p53-dependent apoptosis[1][2][3].
IC50 & Target: Ki: 21 nM (20S proteasome); 35 nM (26 Sproteasome)[1]
In Vitro: MG-115 (0.1-10 μM; 24 h) dose-dependently decreases the viability of HepG2 cells[3].
MG-115 (0.1-10 μM; 24 h) amplifies the reporter gene expression mediated by CWK18 DNA condensates[3].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- MG-115
- Cat. No.:
- HY-108552
- Quantity:
Your information is safe with us.