Debio 0617B
CAS No. : 1332329-27-7
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| Cat. No. : | HY-108417 |
| M.Wt: | 581.98 |
| Formula: | C28H23ClF3N7O2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Debio 0617B, a multi-kinase inhibitor, reduces maintenance and self-renewal of primary human AML CD34+ stem/progenitor cells. Debio 0617B has a unique profile targeting key kinases upstream of STAT3/STAT5 signaling such as JAK, SRC, ABL, and class III/V receptor tyrosine kinases (TKs). Debio 0617B has documented efficacy in STAT3-driven solid tumors[1].
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