| Size | Price | Stock |
|---|---|---|
| 1mg | $55 | In-stock |
| 5mg | $140 | In-stock |
| 10mg | $220 | In-stock |
| 50 mg | Get quote | |
| 100 mg | Get quote | |
| We match the lowest price on market. | ||
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| Cat. No. : | HY-P1192 |
| M.Wt: | 766.00 |
| Formula: | C40H59N7O6S |
| Purity: | >98 % |
| Solubility: | H2O : 1 mg/mL (ultrasonic);DMSO : ≥ 100 mg/mL |
GR-73632 is a tachykinin NK1 receptor agonist. GR-73632 activates spinal NK1 receptors to induce scratching, biting and licking behaviors. GR-73632 activates peripheral NK1 receptors to trigger lacrimation in guinea pigs, and activates central NK1 receptors to induce repetitive hind paw tapping behavior in gerbils. GR-73632 is applicable to research related to pruritus[1][2][3].
IC50 & Target:IC50: NK-1 receptor[1]
In Vivo:GR-73632 (0.1-2.5 pM; intrathecal injection; single administration) acts as a potent spinal NK1 receptor agonist in mice, and induces a dose-dependent syndrome of scratching, biting and licking behaviors[1].
GR-73632 (10-200 nM; intradermal injection; single administration) induces a dose-dependent scratching behavioral response in Mongolian gerbils[2].
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