Bisindolylmaleimide I (Standard)
CAS No. : 133052-90-1
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| Cat. No. : | HY-13867R |
| M.Wt: | 412.48 |
| Formula: | C25H24N4O2 |
| Purity: | >98 % |
| Solubility: |
Bisindolylmaleimide I (Standard) is the analytical standard of Bisindolylmaleimide I. This product is intended for research and analytical applications. Bisindolylmaleimide I (GF109203X) is a cell-permeable and reversible PKC inhibitor (IC50 of 20 nM, 17 nM, 16 nM, and 20 nM for PKCα, PKCβI, PKCβII, and PKCγ. Bisindolylmaleimide I is also a GSK-3 inhibitor[1][2][3]. IC50 & Target:IC50: 20±7 nM (PKC α); 17±5 nM (PKC βI); 16±5 nM (PKC βII); 20±5 nM (PKC γ)[1]
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