Ramosetron (Hydrochloride)
CAS No. : 132907-72-3
(Synonyms: YM060)
| Size | Price | Stock |
|---|---|---|
| 50mg | $120 | In-stock |
| 100mg | $220 | In-stock |
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| Cat. No. : | HY-B0595 |
| M.Wt: | 315.80 |
| Formula: | C17H18ClN3O |
| Purity: | >98 % |
| Solubility: | DMSO : 32 mg/mL (ultrasonic;warming);H2O : 100 mg/mL (ultrasonic) |
Ramosetron (YM060 free base) Hydrochloride is an orally active 5-HT3 antagonist that improves dysphoria, interference with activity and food avoidance. Ramosetron Hydrochloride is promising for research of irritable bowel syndrome with diarrhea[1][2][3][4]. In Vitro:Ramosetron Hydrochloride (1 μM) inhibits 5-HT3 receptor-dependent 5-HT release in guinea pig colonic mucosa[3]. In Vivo:Ramosetron Hydrochloride (0.01-0.1 mg/kg, p.o., twice daily for 5 days) Ameliorates 5-fluorouracil (5-FU) (HY-90006)-induced intestinal mucositis in C57BL/6 mice[2].
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