N-Benzoyl-(2R,3S)-3-phenylisoserine
CAS No. : 132201-33-3
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| Cat. No. : | HY-N2380 |
| M.Wt: | 285.30 |
| Formula: | C16H15NO4 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 160 mg/mL |
N-Benzoyl-(2R,3S)-3-phenylisoserine is the C-13 chiral side chain of paclitaxel and serves as a synthetic scaffold for constructing paclitaxel and related hybrid molecules. N-Benzoyl-(2R,3S)-3-phenylisoserine is used in studies on paclitaxel side chain synthesis and the design of anti-Plasmodium hybrid molecules[1][2][3].
In Vitro:N-Benzoyl-(2R,3S)-3-phenylisoserine (compound 2) exhibits an IC50 >10 μM in erythrocytic-stage assays against the chloroquine-resistant Plasmodium falciparum IndoChina W2 strain[2].
N-Benzoyl-(2R,3S)-3-phenylisoserine exhibits an IC50 >10 μM in erythrocytic stage assays against the multidrug-resistant Plasmodium falciparum Thailand K1 strain[2].
N-Benzoyl-(2R,3S)-3-phenylisoserine exhibits a cytotoxic IC50 >100 μM in L-6 rat skeletal muscle myoblasts[2].
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