BCX-5


CAS No. : 132138-76-2

(Synonyms: PD 141955)

132138-76-2
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Cat. No. : HY-106421
M.Wt: 246.29
Formula: C11H10N4OS
Purity: >98 %
Solubility:
Introduction of 132138-76-2 :

BCX-5 (PD 141955) is an orally active inhibitor of purine nucleoside phosphorylase (PNP) with a Ki of 0.08 μM. BCX-5 can inhibit cell proliferation and mixed lymphocyte reaction. BCX-5 can increase plasma inosine and guanosine levels. BCX-5 can be used for the research of immunology[1][2]. In Vivo:BCX-5 (150 mg/kg, p.o.) produces a elevation of plasma inosine and guanosine in rats[1].

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