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|---|---|---|
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| Cat. No. : | HY-106421 |
| M.Wt: | 246.29 |
| Formula: | C11H10N4OS |
| Purity: | >98 % |
| Solubility: |
BCX-5 (PD 141955) is an orally active inhibitor of purine nucleoside phosphorylase (PNP) with a Ki of 0.08 μM. BCX-5 can inhibit cell proliferation and mixed lymphocyte reaction. BCX-5 can increase plasma inosine and guanosine levels. BCX-5 can be used for the research of immunology[1][2].
In Vivo:BCX-5 (150 mg/kg, p.o.) produces a elevation of plasma inosine and guanosine in rats[1].
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