Penicillin V (Potassium)
CAS No. : 132-98-9
(Synonyms: Phenoxymethylpenicillin (potassium salt))
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| Cat. No. : | HY-B0975 |
| M.Wt: | 388.48 |
| Formula: | C16H17KN2O5S |
| Purity: | >98 % |
| Solubility: | DMSO : 12 mg/mL (ultrasonic);H2O : 6 mg/mL (ultrasonic;warming) |
Penicillin V Potassium (Phenoxymethylpenicillin potassium salt) is an orally active antibiotic. Penicillin V Potassium inhibits the growth of Streptococci, C. difficile and S. aureus. Penicillin V Potassium can be used for the research of otitis, sinusitis, pharyngitis and tonsillitis[1][2][3][4].
In Vitro: Penicillin V (0.002-8.0 mg/L) inhibits the growth of Streptococci, with the minimum inhibitory concentrations (MICs) of 0.004-0.008 mg/L[2].
Penicillin V (0.002-8.0 mg/L) inhibits the growth of C. difficile, with a MIC90 of 8 mg/L[3].
Penicillin V (0.004-0.063 mg/L; 18 h) inhibits the growth of Staphylococcus aureus, with a MIC of 0.016 mg/L[4].
In Vivo: Penicillin V (0.063-0.25 mg/kg; a single s.c.) inhibits the outgrowth of S. aureus in mice thigh muscle[4].
Penicillin V (100 mg/kg; p.o. once daily for 5 d) avoids the fulminant infection of acute purulent otitis media (AOM) in rats[5].
Penicillin V (2 mg/kg; a single s.c.) exhibits the plasma half-life (61 min) and mean AUC (0.47 mg/L•h)[4][4].
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