Umifenovir (hydrochloride)


CAS No. : 131707-23-8

131707-23-8
Price and Availability of CAS No. : 131707-23-8
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5mg $42 In-stock
10mg $66 In-stock
50mg $238 In-stock
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Cat. No. : HY-14904A
M.Wt: 513.88
Formula: C22H26BrClN2O3S
Purity: >98 %
Solubility: DMSO : 25 mg/mL (ultrasonic);H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C)
Introduction of 131707-23-8 :

Umifenovir hydrochloride is a potent, orally active broad-spectrum antiviral with activity against a number of enveloped and non-enveloped viruses. Umifenovir hydrochloride is used as an anti-influenza virus agent. Umifenovir hydrochloride could effectively inhibit the fusion of virus with host cells[1][2]. Umifenovir hydrochloride is an efficient inhibitor of SARS-CoV-2 in vitro. Anti-inflammatory activity[3]. IC50 & Target: Antiviral; Anti-influenza agent In Vitro: Umifenovir hydrochloride exhibits a wide range and potent antiviral activity against a number of viruses including influenza A, B and C viruses, respiratory syncytial virus, adenovirus, parainfluenza type 5 and rhinovirus type 14, avian coronavirus, infectious bronchitis virus and Marek disease virus, hepatitis B virus and hepatitis C virus[1]. In Vivo: Umifenovir (45-180 mg/kg; p.o.; daily for 5 days) suppresses the transcription of influenza viruses (IFV) -associated inflammatory cytokines[2].

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