Olodanrigan
CAS No. : 1316755-16-4
(Synonyms: EMA401; PD-126055; (S)-EMA400)
| Size | Price | Stock |
|---|---|---|
| 5mg | $45 | In-stock |
| 10mg | $68 | In-stock |
| 25mg | $135 | In-stock |
| 50mg | $216 | In-stock |
| 100mg | $321 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-13106 |
| M.Wt: | 507.58 |
| Formula: | C32H29NO5 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 34 mg/mL;H2O : < 0.1 mg/mL |
Olodanrigan (EMA401) is a highly selective, orally active, peripherally restricted angiotensin II type 2 receptor (AT2R) antagonist. It is under development as a neuropathic pain therapeutic agent. Olodanrigan (EMA401) analgesic action appears to involve inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation, and hence inhibition of DRG neuron hyperexcitability and sprouting of DRG neurons[1][2][3][4]. In Vivo: EMA401 (10 mg/kg; p.o.) results in a significant attenuation of theta power and increase in paw withdrawal latencies (PWL) in rats at day 14 after chronic constriction injury (CCI)[4].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- Olodanrigan
- Cat. No.:
- HY-13106
- Quantity:
Your information is safe with us.