| Size | Price | Stock |
|---|---|---|
| 5mg | $140 | In-stock |
| 10mg | $230 | In-stock |
| 25mg | $490 | In-stock |
| 50mg | $820 | In-stock |
| 100mg | $1350 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
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| Cat. No. : | HY-108585 |
| M.Wt: | 404.76 |
| Formula: | C16H13ClN6O5 |
| Purity: | >98 % |
| Solubility: | DMSO : 16.67 mg/mL (ultrasonic);H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) |
VU591 hydrochloride is a potent, selective renal outer medullary potassium channel (ROMK or Kir1.1) inhibitor, with an IC50 of 0.24 μM. VU591 hydrochloride can be used for neurological research with HY-108585A (the equivalent of VU591 hydrochloride)[1]. IC50 & Target: IC50: 0.24 μM (ROMK)[1]. In Vitro: VU591 hydrochloride is a selective ROMK inhibitor and a ROMK channel pore blocker. VU591 can bind serum protein and has high metabolic stability[1]. In Vivo: VU591 hydrochloride (i.c.v.; 1.842 μg) significantly decreases the immobile time in TST[2].
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