VU591 hydrochloride


CAS No. : 1315380-70-1

1315380-70-1
Price and Availability of CAS No. : 1315380-70-1
Size Price Stock
5mg $140 In-stock
10mg $230 In-stock
25mg $490 In-stock
50mg $820 In-stock
100mg $1350 In-stock
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Cat. No. : HY-108585
M.Wt: 404.76
Formula: C16H13ClN6O5
Purity: >98 %
Solubility: DMSO : 16.67 mg/mL (ultrasonic);H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C)
Introduction of 1315380-70-1 :

VU591 hydrochloride is a potent, selective renal outer medullary potassium channel (ROMK or Kir1.1) inhibitor, with an IC50 of 0.24 μM. VU591 hydrochloride can be used for neurological research with HY-108585A (the equivalent of VU591 hydrochloride)[1]. IC50 & Target: IC50: 0.24 μM (ROMK)[1]. In Vitro: VU591 hydrochloride is a selective ROMK inhibitor and a ROMK channel pore blocker. VU591 can bind serum protein and has high metabolic stability[1]. In Vivo: VU591 hydrochloride (i.c.v.; 1.842 μg) significantly decreases the immobile time in TST[2].

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