TAK1/MAP4K2 inhibitor 1


CAS No. : 1315330-11-0

1315330-11-0
Price and Availability of CAS No. : 1315330-11-0
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5mg $370 In-stock
10mg $475 In-stock
50mg $1280 In-stock
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Cat. No. : HY-77251
M.Wt: 552.59
Formula: C29H31F3N6O2
Purity: >98 %
Solubility: DMSO : 50 mg/mL (ultrasonic)
Introduction of 1315330-11-0 :

TAK1/MAP4K2 inhibitor 1 is a potent dual TGFβ-activated kinase 1 (TAK1) and mitogen-activated protein kinase kinase kinase kinase 2 (MAP4K2) inhibitor, with IC50s of 41.1 nM and 18.2 nM, respectively. In Vivo: TAK1/MAP4K2 inhibitor 1 has moderate terminal elimination half-life (t1/2=2.94 h for mice (1 mg/kg, iv))[1].

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