UNC 669
CAS No. : 1314241-44-5
| Size | Price | Stock |
|---|---|---|
| 5mg | $37 | In-stock |
| 10mg | $60 | In-stock |
| 50mg | $135 | In-stock |
| 100mg | $250 | In-stock |
| 200mg | $375 | In-stock |
| 500mg | $750 | In-stock |
| 1 g | Get quote | |
| 5 g | Get quote | |
| We match the lowest price on market. | ||
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| Cat. No. : | HY-15839 |
| M.Wt: | 338.24 |
| Formula: | C15H20BrN3O |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
UNC 669, a ligand for a methyl-lysine binding domain, is a potent L3MBTL1 (IC50=4.2 uM) and L3MBTL3 (3.1 uM) inhibitor[1]. IC50 & Target: IC50: 4.2 uM/3.1 uM (L3MBTL1/L3MBTL3)[1] In Vitro: L3MBTL1, a paralogue of Drosophila tumor suppressor lethal(3)malignant brain tumor (l(3)mbt), binds histones in a methylation state-dependent manner and contributes to higher order chromatin structure and transcriptional repression. Similar to L3MBTL1, the closely related protein, L3MBTL3, also contains three MBT repeats and has been shown to play a role in meduloblastoma formation and normal hematopoiesis in humans[1][2].
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- UNC 669
- Cat. No.:
- HY-15839
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