MK2-IN-1
CAS No. : 1314118-92-7
| Size | Price | Stock |
|---|---|---|
| 5mg | $65 | In-stock |
| 10mg | $110 | In-stock |
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| Cat. No. : | HY-12834 |
| M.Wt: | 472.97 |
| Formula: | C27H25ClN4O2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
MK2-IN-1 (compound 1) is a potent and selecitve MAPKAPK2 (MK2) inhibitor with an IC50 of 0.11 uM for MK2 and an EC50 of 0.35 uM for pHSP27. MK2-IN-1 impaires the phosphorylation level of serine residues in the Tfcp2l1 protein[1][2].
In Vitro:MK2-IN-1 (purchased from MCE; 5 μM; 0.5-8 h) gradually increases Tfcp2l1 protein level without a change in the Tfcp2l1 transcript level within 2 h[2].
MK2-IN-1 induces more alkaline phosphatase (AP)-positive colonies than the other factors in a short time[2].
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