VUT-MK142


CAS No. : 1313491-22-3

1313491-22-3
Price and Availability of CAS No. : 1313491-22-3
Size Price Stock
5mg $240 In-stock
10mg $360 In-stock
25mg $720 In-stock
50mg $1000 In-stock
100mg $1600 In-stock
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Cat. No. : HY-122610
M.Wt: 298.38
Formula: C17H22N4O
Purity: >98 %
Solubility: DMSO : 25 mg/mL (ultrasonic)
Introduction of 1313491-22-3 :

VUT-MK142 is a potent new cardiomyogenic synthetic agent promoting the differentiation of pre-cardiac mesoderm into cardiomyocytes, which may be useful to differentiate stem cells into cardiomyocytes for cardiac repair[1]. In Vitro: VUT-MK142 possesses promising cardiomyogenic effects on various cell types. VUT-MK142 shows a remarkable effect on both P19 and C2C12 cells. Compared to CgC, VUT-MK142-treatment leads to a markedly stronger up-regulation of the expression of ANF[1].
VUT-MK142 (1 μM, 7 day treatment) significantly (p < 0.05) increases the luciferase signal by 3.1 ± 0.3 luciferase (n = 5)-fold in P19 cells[1].

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