DNQX (disodium salt)
CAS No. : 1312992-24-7
(Synonyms: FG 9041 (disodium salt))
| Size | Price | Stock |
|---|---|---|
| 5mg | $100 | In-stock |
| 10mg | $150 | In-stock |
| 25mg | $270 | In-stock |
| 50mg | $432 | In-stock |
| 100mg | $606 | In-stock |
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| Cat. No. : | HY-103233 |
| M.Wt: | 296.10 |
| Formula: | C8H2N4Na2O6 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
DNQX (FG 9041) disodium salt, a quinoxaline derivative, is a selective, potent competitive non-NMDA glutamate receptor antagonist (IC50s = 0.5, 2 and 40 μM for AMPA, kainate and NMDA receptors, respectively)[1]. IC50 & Target:Non-NMDA Receptor[1] In Vitro: DNQX (FG 9041) disodium salt selectively depolarizes thalamic reticular nucleus (TRN) neurons[2]. In Vivo: DNQX (FG 9041), a specific AMPA receptor antagonist, given as either a 5 mg/kg or 10 mg/kg intraperitoneal dose or into the lateral cerebral ventricle (5 μl of 0.5 mg/ml) significantly diminishes phencyclidine (PCP) (40 mg/kg) and ketamine (80, 100, 120 mg/kg) hsp70 induction in the posterior cingulate and retrosplenial cortex[3].
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