5,7-Dichlorokynurenic acid (Standard)
CAS No. : 131123-76-7
(Synonyms: 5,7-DCKA (Standard))
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| Cat. No. : | HY-100834R |
| M.Wt: | 258.06 |
| Formula: | C10H5Cl2NO3 |
| Purity: | >98 % |
| Solubility: |
5,7-Dichlorokynurenic acid (Standard) is the analytical standard of 5,7-Dichlorokynurenic acid (HY-100834). This product is intended for research and analytical applications. 5,7-Dichlorokynurenic acid (5,7-DCKA) is a selective and competitive antagonist of the glycine site on NMDA receptor with a KB of 65 nM. 5,7-Dichlorokynurenic acid reduces NMDA-induced neuron injury. 5,7-Dichlorokynurenic acid increases social interaction time, increases open arm exploration time, disinhibits suppressed conflict responding in rodent models. 5,7-Dichlorokynurenic acid exhibits anxiolytic-like activity in rodent models and supports exploration of glycine’s role in NMDA receptor-mediated synaptic transmission[1][2].
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