Upadacitinib (Standard)


CAS No. : 1310726-60-3

(Synonyms: ABT-494 (Standard))

1310726-60-3
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Cat. No. : HY-19569R
M.Wt: 380.37
Formula: C17H19F3N6O
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 1310726-60-3 :

Upadacitinib (Standard) is the analytical standard of Upadacitinib. Upadacitinib (ABT-494) is a potent, orally active and selective Janus kinase 1 (JAK1) inhibitor (IC50=43 nM). Upadacitinib (ABT-494) displays approximately 74 fold selective for JAK1 over JAK2 (200 nM) in cellular assays dependent on specific, relevant cytokines. Upadacitinib (ABT-494) can be used for several autoimmune disorders research [1].

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