Deserpidine


CAS No. : 131-01-1

(Synonyms: Harmonyl)

131-01-1
Price and Availability of CAS No. : 131-01-1
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25mg $420 In-stock
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Cat. No. : HY-107339
M.Wt: 578.65
Formula: C32H38N2O8
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 131-01-1 :

Deserpidine (Harmonyl) is an alkaloid isolated from the root of Rauwolfia canescens related to Reserpine. Deserpidine is used as an antihypertensive agent and a tranquilizer. Deserpidine is a competitive angiotensin converting enzyme (ACE) inhibitor. Deserpidine also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex[1][2][3]. IC50 & Target:Angiotensin converting enzyme (ACE)[3] In Vitro: Deserpidine is an effective ganglionic blocking agent, which differs from Reserpine only by the absence of a methoxy group at C-11. Deserpidine has been used in the treatment of hypertension and psychosis. In addition, Deserpidine appears to act as a controller of other cardiac disorders[1][2].

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