Decloxizine (dihydrochloride)


CAS No. : 13073-96-6

(Synonyms: UCB 1402 (dihydrochloride); NSC289116 (dihydrochloride))

13073-96-6
Price and Availability of CAS No. : 13073-96-6
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Cat. No. : HY-A0075
M.Wt: 413.38
Formula: C21H30Cl2N2O2
Purity: >98 %
Solubility: DMSO : ≥ 50 mg/mL;H2O : ≥ 100 mg/mL
Introduction of 13073-96-6 :

Decloxizine (UCB-1402; NSC289116) dihydrochloride is an orally active bronchodilator that can penetrate the blood-brain barrier. Decloxizine dihydrochloride is a piperazine-type H1 histamine receptor antagonist. Decloxizine dihydrochloride selectively blocks H1 histamine receptors, inhibiting histamine-induced capillary dilation, edema, and itching. Decloxizine dihydrochloride has some 5-HT2 receptor antagonistic activity. Decloxizine dihydrochloride can be used in studies of urticaria, allergic rhinitis, and bronchial asthma[1][2][3]. In Vitro:Decloxizine dihydrochloride has an inhibitory effect on bronchial contraction induced by histamine aerosol in conscious guinea pigs[1].

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