DA 1686
CAS No. : 13071-27-7
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| Cat. No. : | HY-120730 |
| M.Wt: | 368.51 |
| Formula: | C23H32N2O2 |
| Purity: | >98 % |
| Solubility: |
DA 1686 is an orally active naphthalene derivative that induces bradycardia and mild hypotension. DA 1686 can be used in the study of arrhythmias[1].
In Vitro:DA 1686 reduces aconitine-induced tachycardia and responsiveness to increased electrical stimulation in isolated guinea-pig auricles[1].
In Vivo:DA 1686 exhibits local anaesthetic activity in in vivo mouse and guinea-pig models[1].
DA 1686 (20 mg/kg; i.v.; slow infusion) protects anaesthetized dogs from Adrenaline (HY-B0447)-induced death during benzol inhalation[1].
DA 1686 protects rats from arrhythmia induced by intravenous administration of 34 μg/kg Aconitine[1].
DA 1686 delays the onset of Ouabain (HY-B1457)-induced arrhythmia, ventricular fibrillation, and cardiac arrest in guinea-pigs[1].
DA 1686 reduces tachycardia induced by 10 days of daily 0.2 mg Thyroxine (HY-18341) administration in rabbits[1].
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