MI-773
CAS No. : 1303607-07-9
| Size | Price | Stock |
|---|---|---|
| 5mg | $156 | In-stock |
| 10mg | $252 | In-stock |
| 25mg | $529 | In-stock |
| 50mg | $972 | In-stock |
| 100mg | $1800 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-17493 |
| M.Wt: | 562.50 |
| Formula: | C29H34Cl2FN3O3 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 53 mg/mL |
MI-773 is an orally active, selective MDM2-p53 interaction inhibitor with a Ki of 0.88 nM for MDM2. MI-773 blocks the MDM2-TP53 interaction. MI-773 potently activates p53. MI-773 induces Apoptosis. MI-773 causes tumor regression in xenograft models of adenoid cystic carcinoma. MI-773 exhibits anticancer effects in neuroblastoma. MI-773 TFA can be used for the research of adenoid cystic carcinoma[1][2].
In Vivo:MI-773 (10-100 mg/kg; p.o.; daily) induces dose-dependent tumor growth inhibition and regression in the UM-PDX-HACC-5 adenoid cystic carcinoma model, with 100 mg/kg mediating a 127% TGI index and 86% tumor shrinkage via p53-dependent apoptosis[1].
MI-773 (100 mg/kg; p.o.; daily) mediates significant tumor regression in the ACCx6 adenoid cystic carcinoma PDX model[1].
MI-773 (100 mg/kg; p.o.; daily) mediates significant tumor regression in the ACCx9 adenoid cystic carcinoma PDX model[1].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- MI-773
- Cat. No.:
- HY-17493
- Quantity:
Your information is safe with us.