MI-773
CAS No. : 1303607-07-9
| Size | Price | Stock |
|---|---|---|
| 5mg | $156 | In-stock |
| 10mg | $252 | In-stock |
| 25mg | $529 | In-stock |
| 50mg | $972 | In-stock |
| 100mg | $1800 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-17493 |
| M.Wt: | 562.50 |
| Formula: | C29H34Cl2FN3O3 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 53 mg/mL |
MI-773 is a potent MDM2-p53 protein‐protein interaction (PPI) inhibitor with high binding affinity against MDM2 (Kd=8.2 nM). MI-773 has antitumor activity[1][2].
In Vitro: SAR405838 (MI-77301), an analog of MI-773, displays 10 times higher binding affinity against MDM2 than MI-773 (Kd=62 vs 8.2 nM). The antitumor activity of MI-77301 is more pronounced in a set of wild type p53 xenograft models than MI-773, including SJSA-1 osteosarcoma, human prostate, melanoma, colorectal tumor, LNCAP human prostate tumor and human acute lymphoblastic leukemia[1].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- MI-773
- Cat. No.:
- HY-17493
- Quantity:
Your information is safe with us.