5α-Hydroxy-6-keto cholesterol


CAS No. : 13027-33-3

13027-33-3
Price and Availability of CAS No. : 13027-33-3
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Cat. No. : HY-123349
M.Wt: 418.65
Formula: C27H46O3
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 13027-33-3 :

5α-Hydroxy-6-keto cholesterol is major metabolite of β-epoxide (5α,6β-epoxycholesterol) during direct exposure of intact cultured human bronchial epithelial cells (16-HBE) to ozone. 5α-Hydroxy-6-keto cholesterol inhibits cholesterol synthesis with an IC50 of 350 nM[1]. In Vitro: 5α-Hydroxy-6-keto cholesterol (0.01, 0.1, 1, 10 μM) is cytotoxic to cultured 16-HBE cells[1].

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