Torilin


CAS No. : 13018-10-5

13018-10-5
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Cat. No. : HY-N1140
M.Wt: 376.49
Formula: C22H32O5
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 13018-10-5 :

Torilin is a sesquiterpene with antimicrobial, anticancer, and anti-inflammatory properties. Torilin inhibits LPS-induced NO release, as well as inhibiting iNOS, PGE2, COX-2, NF-α, IL-1β, IL-6, and GM-CSF. Torilin suppresses NF-kB and AP-1 translocation, inhibits TAK1 kinase activation. Subsequently results suppression of MAPK-mediated JNK, p38, ERK1/2, and AP-1 (ATF-2 and c-jun) activation and IKK-mediated I-κBα degradation, p65/p50 activation, and translocation[1].

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