Eberconazole nitrate
CAS No. : 130104-32-4
| Size | Price | Stock |
|---|---|---|
| 5mg | $80 | In-stock |
| 10mg | $130 | In-stock |
| 25mg | $260 | In-stock |
| 50mg | $390 | In-stock |
| 100mg | $590 | In-stock |
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| Cat. No. : | HY-106542A |
| M.Wt: | 392.24 |
| Formula: | C18H15Cl2N3O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 250 mg/mL (ultrasonic) |
Eberconazole nitrate is a dichlorinated imidazole derivative with antifungal activity. Eberconazole nitrate is more effective than Clotrimazole (HY-10882), Ketoconazole (HY-B0105), and Miconazole (HY-B0454). Eberconazole nitrate has potential for the study of dermatophytosis[1][2]. In Vitro:Eberconazole (0.03-2 μg/mL, 7 days) exhibits significant antifungal activity against 200 strains of dermatophytes, with the strongest activity against Trichophyton rubrum and Trichophyton mentagrophytes[1]. In Vivo:Eberconazole (1%-1.3% Eberconazole cream, approximately 1-1.3 g per animal, topical application, twice daily for 6 days) demonstrated significant therapeutic efficacy in the experimentally induced cutaneous candidiasis guinea pig model, with 90% of guinea pigs showing negative culture results from infected skin samples and lesion disappearance, superior to Clotrimazole (HY-10882)[2].
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