I-BET762 carboxylic acid


CAS No. : 1300019-38-8

(Synonyms: Molibresib carboxylic acid; GSK525762A carboxylic acid; PROTAC BRD4-binding moiety 2)

1300019-38-8
Price and Availability of CAS No. : 1300019-38-8
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5mg $80 In-stock
10mg $130 In-stock
25mg $270 In-stock
50mg $460 In-stock
100mg $785 In-stock
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Cat. No. : HY-107443
M.Wt: 396.83
Formula: C20H17ClN4O3
Purity: >98 %
Solubility: DMSO : 7.14 mg/mL (ultrasonic)
Introduction of 1300019-38-8 :

I-BET762 carboxylic acid (Molibresib carboxylic acid) is an I-BET762-based warhead ligand for conjugation reactions of PROTAC targeting on BET. I-BET762 carboxylic acid (Molibresib carboxylic acid) is a BRD4 inhibitor with a pIC50 of 5.1[1]. IC50 & Target: pIC50: 5.1 (BRD4)[1] In Vitro: I-BET762 carboxylic acid (Molibresib carboxylic acid) (Compound 27) inhibits peripheral blood mononuclear cells (PBMC) with a pIC50 of <4[1].

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