CAS No. : 1300019-38-8
(Synonyms: Molibresib carboxylic acid; GSK525762A carboxylic acid; PROTAC BRD4-binding moiety 2)
| Size | Price | Stock |
|---|---|---|
| 5mg | $80 | In-stock |
| 10mg | $130 | In-stock |
| 25mg | $270 | In-stock |
| 50mg | $460 | In-stock |
| 100mg | $785 | In-stock |
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| Cat. No. : | HY-107443 |
| M.Wt: | 396.83 |
| Formula: | C20H17ClN4O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 7.14 mg/mL (ultrasonic) |
I-BET762 carboxylic acid (Molibresib carboxylic acid) is an I-BET762-based warhead ligand for conjugation reactions of PROTAC targeting on BET. I-BET762 carboxylic acid (Molibresib carboxylic acid) is a BRD4 inhibitor with a pIC50 of 5.1[1]. IC50 & Target: pIC50: 5.1 (BRD4)[1] In Vitro: I-BET762 carboxylic acid (Molibresib carboxylic acid) (Compound 27) inhibits peripheral blood mononuclear cells (PBMC) with a pIC50 of <4[1].
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