Pamoic acid
CAS No. : 130-85-8
(Synonyms: Embonic acid)
| Size | Price | Stock |
|---|---|---|
| 1g | $25 | In-stock |
| 5g | $42 | In-stock |
| 10g | $55 | In-stock |
| 25g | $77 | In-stock |
| 50g | $100 | In-stock |
| 100g | $120 | In-stock |
| 200 g | Get quote | |
| 500 g | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-W008613 |
| M.Wt: | 388.38 |
| Formula: | C23H16O6 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
Pamoic acid (Embonic acid) is a potent GPR35 agonist with an EC50 of 79 nM. Pamoic acid exhibits neuroprotective and anti-inflammatory properties[1][2]. IC50 & Target:EC50: 79 nM (GPR35)[1] In Vitro:GPR35 activation by Pamoic acid may increase the phosphorylation of ERK1/2, which in turn initiates an anti-inflammatory signal by suppressing NF-κB-dependent inflammatory genes[1]. In Vivo:In a mouse model of stroke, Pamoic acid (s.c.; 50-100 mg/kg) has neuroprotective activity that activates GPR35. Pharmacological inhibition of GPR35 reveals that Pamoic acid reduces infarcts size in a GPR35 dependent manner. Pamoic acid treatment results in a preferential increment of noninflammatory Ly-6CLo monocytes/macrophages in the ischemic brain along with the reduced neutrophil counts[1].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- Pamoic acid
- Cat. No.:
- HY-W008613
- Quantity:
Your information is safe with us.