Cloxiquine
CAS No. : 130-16-5
(Synonyms: 5-Chloro-8-quinolinol)
| Size | Price | Stock |
|---|---|---|
| 100g | $19 | In-stock |
| 500g | $73 | In-stock |
| 1000g | $120 | In-stock |
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| Cat. No. : | HY-B0963 |
| M.Wt: | 179.61 |
| Formula: | C9H6ClNO |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Cloxiquine (5-Chloro-8-quinolinol) is an antibacterial, antifungal and antiamoebic agent. Cloxiquine can be used for the research of tuberculosis and dermatoses. Cloxiquine suppresses the growth and metastasis of melanoma cells through activation of PPARγ[1][2].
In Vitro: Cloxiquine (cloxyquin) exhibits antituberculosis activities, with MICs ranging from 0.062 to 0.25 μg/mL against 9 standard strains and 150 Mycobacterium tuberculosis[3].
Cloxiquine (0.5-10 μM; 24 h) suppresses both B16F10 and A375 cell growth in a dose-dependent manner[2].
Cloxiquine (0.5-10 μM; 24 h) inhibits the migration of B16F10 and A375 cells[2].
Cloxiquine (0.5-2.5 μM; 24 h) suppresses glycolysis in B16F10 cells[2].
In Vivo: Cloxiquine (5-25 mg/kg; i.p. daily for 8 d) suppresses tumor growth in a mouse B16F10 melanoma xenograft model[2].
Cloxiquine (5-25 mg/kg; i.p. daily for 14 d) suppresses tumor metastasis in mouse B16F10 melanoma lung metastatic model[2].
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