Y-27632 (dihydrochloride) (GMP)
CAS No. : 129830-38-2
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| Cat. No. : | HY-10583G |
| M.Wt: | 320.26 |
| Formula: | C14H23Cl2N3O |
| Purity: | >98 % |
| Solubility: | H2O : 100 mg/mL (ultrasonic) |
Y-27632 dihydrochloride (GMP) is the GMP level of Y-27632 dihydrochloride (HY-10583). GMP guidelines are used to produce Y-27632 dihydrochloride (GMP). GMP small molecules works appropriately as an auxiliary reagent for cell research manufacture. Y-27632 dihydrochloride is an orally active and ATP-competitive ROCK (Rho-kinase) inhibitor with antiepileptic effect[1][2][3][4]. In Vitro: Y-27632 dihydrochloride (GMP) (2 μM; 4-8 d) enhances the survival rate and inreases reprogramming of mouse fibroblasts directly converted into neuronal cells[1]. Y-27632 dihydrochloride (GMP) induces human fibroblasts convert into functional cardiomyocytes[2]. Y-27632 dihydrochloride (GMP) induces fibroblasts convert into pluripotent stem cells (hiPSCs)[2]. Y-27632 dihydrochloride (GMP) (2-10 μM) promotes human EPS cell proliferation and induces primed hPSCs convert into hEPS cells[3]. Y-27632 dihydrochloride (GMP) (10 μM) induces human EPS cell derivated from blastocysts[4].
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