Aripiprazole
CAS No. : 129722-12-9
(Synonyms: OPC-14597)
| Size | Price | Stock |
|---|---|---|
| 100mg | $79 | In-stock |
| 200mg | $99 | In-stock |
| 500mg | $139 | In-stock |
| 1g | $178 | In-stock |
| 5g | $578 | In-stock |
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| Cat. No. : | HY-14546 |
| M.Wt: | 448.39 |
| Formula: | C23H27Cl2N3O2 |
| Purity: | >98 % |
| Solubility: | DMF : 50 mg/mL (ultrasonic);DMSO : ≥ 100 mg/mL |
Aripiprazole (OPC-14597), an atypical antipsychotic, is a potent and high-affinity dopamine D2 receptor partial agonist. Aripiprazole is an inverse agonist at 5-HT2B and 5-HT2A receptors and displays partial agonist actions at 5-HT1A, 5-HT2C, D3, and D4 receptors. Aripiprazole can be used for the research of schizophrenia and COVID19[1][2][3][4].
In Vitro: Aripiprazole potently activates D2 receptor-mediated inhibition of cAMP accumulation[1].
Aripiprazole shows a greater anti-inflammatory effect on TNF-α, IL-13, IL-17α and fractalkine[3].
In Vivo: Aripiprazole (0-3 mg/kg, IP, daily) shows some anxiolytic properties[4].
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