RV-1729
CAS No. : 1293915-42-0
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| Cat. No. : | HY-106006 |
| M.Wt: | 735.23 |
| Formula: | C39H39ClN8O5 |
| Purity: | >98 % |
| Solubility: |
RV-1729 is an inhibitor of the phosphatidylinositol 3-kinase-δ (PI3Kδ). RV-1729 identifies inhibition of the PI3K isotype by quantifying the release of phosphatidylinositol 3,4, 5-triphosphate (PIP3) (IC50=12 nM), showing twice the selectivity for PI3Kδ relative to PI3Kγ. RV-1729 is also 16 times more selective to PI3Kα. RV-1729 regulates immune and inflammatory responses by inhibiting PI3Kδ. RV-1729 can be used in studies of asthma and chronic obstructive pulmonary disease (COPD)[1].
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- RV-1729
- Cat. No.:
- HY-106006
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