Licorisoflavan A
CAS No. : 129314-37-0
(Synonyms: 7-O-Methyllicorisoflavan B)
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| Cat. No. : | HY-N3385 |
| M.Wt: | 438.56 |
| Formula: | C27H34O5 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Licorisoflavan A (7-O-Methyllicorisoflavan B) is a isoflavan-quinone, that can be isolated from Glycyrrhiza uralensis[1]. Licorisoflavan A exhibits anti-inflammatory and antimicrobial properties[2][3]. It can inhibit the secretion of IL-6 and chemokines by LPS-stimulated macrophages in a concentration-dependent manner, and also suppress the secretion of MMP-7, MMP-8, and MMP-9 in macrophages[4]. Licorisoflavan A exertes potent antidepressant-like effects involving BDNF-TrkB pathway and AMPA receptors[5].
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