Lurosetron
CAS No. : 128486-54-4
(Synonyms: GR-87442)
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| Cat. No. : | HY-106379 |
| M.Wt: | 312.34 |
| Formula: | C17H17FN4O |
| Purity: | >98 % |
| Solubility: |
Lurosetron (GR-87442) is a 6-fluoro analogue of Alosetron (HY-70050A). Lurosetron is a serotonin 5-HT3 receptor antagonist. Lurosetron inhibits recombinant (rbt) CYP1A2, with an IC50 of 0.1 μM. Lurosetron also inhibits other CYP isoforms, including rbtCYP2C9 and rbtCYP3A4 with IC50s ranging between 3.5 μM and 16 μM.[1].
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