CAS No. : 128-13-2
(Synonyms: Ursodeoxycholate (Standard); Ursodiol (Standard); UDCA (Standard))
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| Cat. No. : | HY-13771R |
| M.Wt: | 392.57 |
| Formula: | C24H40O4 |
| Purity: | >98 % |
| Solubility: |
Ursodeoxycholic acid (Standard) is the analytical standard of Ursodeoxycholic acid. This product is intended for research and analytical applications. Ursodeoxycholic acid (Ursodeoxycholate) is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. Ursodeoxycholic acid acts as signaling molecule, exerting its effects by interacting with bile acid activated receptors, including G-protein coupled bile acid receptor 5 (TGR5, GPCR19) and the farnesoid X receptor (FXR). Ursodeoxycholic acid can be used for the research of a variety of hepatic and gastrointestinal diseases. Ursodeoxycholic acid also reduces ACE2 expression and is beneficial for reducing SARS-CoV-2 infection. Orally active[1][2][3][4].
IC50 & Target:FATP5[3]
ACE2[4]
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