Ursodeoxycholic acid (Standard)


CAS No. : 128-13-2

(Synonyms: Ursodeoxycholate (Standard); Ursodiol (Standard); UDCA (Standard))

128-13-2
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Cat. No. : HY-13771R
M.Wt: 392.57
Formula: C24H40O4
Purity: >98 %
Solubility:
Introduction of 128-13-2 :

Ursodeoxycholic acid (Standard) is the analytical standard of Ursodeoxycholic acid. This product is intended for research and analytical applications. Ursodeoxycholic acid (Ursodeoxycholate) is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. Ursodeoxycholic acid acts as signaling molecule, exerting its effects by interacting with bile acid activated receptors, including G-protein coupled bile acid receptor 5 (TGR5, GPCR19) and the farnesoid X receptor (FXR). Ursodeoxycholic acid can be used for the research of a variety of hepatic and gastrointestinal diseases. Ursodeoxycholic acid also reduces ACE2 expression and is beneficial for reducing SARS-CoV-2 infection. Orally active[1][2][3][4]. IC50 & Target:FATP5[3]
ACE2[4]

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