SGK1-IN-1


CAS No. : 1279829-87-6

1279829-87-6
Price and Availability of CAS No. : 1279829-87-6
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5mg $300 In-stock
10mg $480 In-stock
25mg $950 In-stock
50mg $1520 In-stock
100mg $2250 In-stock
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Cat. No. : HY-18607
M.Wt: 418.83
Formula: C17H12ClFN6O2S
Purity: >98 %
Solubility: DMSO : 50 mg/mL (ultrasonic)
Introduction of 1279829-87-6 :

SGK1-IN-1 is a highly active and selective inhibitor of SGK-1, with an IC50 of 1 nM. IC50 & Target: IC50: 1 nM (SGK-1)[1][2]. In Vitro: SGK1-IN-1 (14n) shows an acceptable SGK isoform selectivity with a good activity on hSGK2 and a moderate activity on the hSGK3, with IC50s of 1, 41 nM at 10 μM and 50 μM ATP concentration, respectively. SGK1-IN-1 also displays cellular activity in a SGK1-dependent phosphorylation of GSK3β assay in U2OS cells with activities of 0.69 μM[2].

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