CU-CPT 4a
CAS No. : 1279713-77-7
(Synonyms: TLR3-IN-1)
| Size | Price | Stock |
|---|---|---|
| 5mg | $143 | In-stock |
| 10mg | $242 | In-stock |
| 25mg | $484 | In-stock |
| 50mg | $678 | In-stock |
| 100mg | $950 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-108473 |
| M.Wt: | 377.82 |
| Formula: | C18H13ClFNO3S |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
CU-CPT 4a (TLR3-IN-1) is a potent, highly selective TLR3 signaling inhibitor. CU-CPT 4a represses the expression of downstream signaling pathways mediated by the TLR3/dsRNA complex, including TNF-α and IL-1β[1].
IC50 & Target: IC50: 3.44 µM (TLR3, in RAW 264.7 cells)[1]
In Vitro: CU-CPT 4a shows dose-dependent inhibitory effects blocking Poly (I:C)-induced TLR3 activation with an IC50 of 3.44 µM[1].
CU-CPT 4a competes with dsRNA for binding to TLR3 with a Ki of 2.96 µM[1].
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