Discodermolide


CAS No. : 127943-53-7

(Synonyms: NVP-XAA-296; XAA 296)

127943-53-7
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Cat. No. : HY-105409
M.Wt: 593.79
Formula: C33H55NO8
Purity: >98 %
Solubility:
Introduction of 127943-53-7 :

Discodermolide is a potent microtubule-stabilizing agent with a Ki of 0.4 μM. Discodermolide stabilizes microtubules, induces G2 or M phase cell cycle arrest and apoptosis, leading to inhibition of cancer cell proliferation. Discodermolide competitively inhibits the binding of Paclitaxel (HY-B0015) to tubulin polymers, and inhibits the growth of Paclitaxel-resistant cells. Discodermolide can be used for breast and colon cancer research[1][2][3].

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