Saquinavir
CAS No. : 127779-20-8
(Synonyms: Ro 31-8959)
| Size | Price | Stock |
|---|---|---|
| 5mg | $42 | In-stock |
| 10mg | $66 | In-stock |
| 25mg | $150 | In-stock |
| 50mg | $252 | In-stock |
| 100mg | $396 | In-stock |
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| Cat. No. : | HY-17007 |
| M.Wt: | 670.84 |
| Formula: | C38H50N6O5 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Saquinavir (Ro 31-8959) is an orally active HIV protease inhibitor that can be used in the research of AIDS. Saquinavir also has anti-inflammatory activity and can induce apoptosis of human red blood cells[1][2][3].
In Vitro:Saquinavir (2.5-15 μg/mL; 48 h) can induce the apoptosis of human red blood cells, and the mechanism involves the generation of ROS and the influx of Ca2+[1].
In Vivo:Saquinavir (250-2500 mg/kg; administered via diet; 1 month) exhibits anti-HIV activity in the thy/liv-SCID-hu mouse model[2].
Saquinavir (0.5 mg/kg; twice) has a protective effect in the mouse model of lung injury induced by hepatic ischemia-reperfusion (I/R)[3].
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