L-674573
CAS No. : 127481-29-2
| Size | Price | Stock |
|---|---|---|
| 5mg | $66 | In-stock |
| 10mg | $105 | In-stock |
| 25mg | $205 | In-stock |
| 50mg | $325 | In-stock |
| 100mg | $520 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-120571 |
| M.Wt: | 457.58 |
| Formula: | C28H27NO3S |
| Purity: | >98 % |
| Solubility: | DMSO : 125 mg/mL (ultrasonic) |
L-674573 is a quinoline leukotriene synthesis inhibitor, inhibiting Calcimycin (HY-N6687)- and N-Formyl-Met-Leu-Phe (HY-P0224)-induced leukotriene production with IC50s of 100 nM and 50 nM, respectively. L-674573 selectively inhibits Calcimycin- and N-Formyl-Met-Leu-Phe-induced 5-lipoxygenase translocation[1]. In Vitro:L-674573 (1 μM) inhibits the Calcimycin (A23187)-induced translocation of 5-lipoxygenase to membranes in HL-60 cells[1].
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