Conantokin-T
CAS No. : 127476-26-0
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| Cat. No. : | HY-P1287 |
| M.Wt: | 2683.81 |
| Formula: | C110H175N31O45S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Conantokin-T is a γ-carboxyglutamate-containing, N-methyl-D-aspartate (NMDA) antagonist peptidewith an IC50 value of 2 μM. Conantokin-T inhibits NMDA receptor-mediated calcium influx in central nervous system neurons. Conantokin-T can be purified from the venom of the fish-hunting cone snail, Conus tulipa[1]. IC50 & Target:IC50: 2 μM (NMDA)[1] In Vitro: Conantokin-T produces a partial antagonism of NMDA receptor function with an IC50 value of 2 μM[1]. In Vivo: Conantokin-T induces sleep-like symptoms in young mice[1].
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