Balofloxacin
CAS No. : 127294-70-6
(Synonyms: Q-35)
| Size | Price | Stock |
|---|---|---|
| 250mg | $35 | In-stock |
| 500mg | $56 | In-stock |
| 1g | $85 | In-stock |
| 5g | $214 | In-stock |
| 10g | $300 | In-stock |
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| Cat. No. : | HY-B0159 |
| M.Wt: | 389.42 |
| Formula: | C20H24FN3O4 |
| Purity: | >98 % |
| Solubility: | DMSO : 0.67 mg/mL (ultrasonic);H2O : < 0.1 mg/mL |
Balofloxacin (Q-35) is an orally active fluoroquinolone antibiotic with broad-spectrum antibacterial activity against gram-negative, gram-positive, and anaerobic bacteria. Balofloxacin can be used for the research of respiratory, intestinal, and urinary tract infections[1][2].
In Vitro: Balofloxacin (25 mg/mL; 1 h) decreases the growth of S. aureus that adhered to human corneal epithelial cells (HCECs)[2].
Balofloxacin inhibits the S. aureus ATCC 25923, with a MIC of 0.125 mg/mL[2].
Balofloxacin (0.05-500 μg/mL; 72 h) does not induce toxicity on the HCECs at a low concentration, such as 0.625 mg/mL[2].
In Vivo: Balofloxacin (200 mg/kg/day; p.o. for 5 d) reduces the counts of viable M. pneumonia in the lungs of hamsters[3].
Balofloxacin eye drops (0.5%) is effective in S. aureus bacterial keratitis of rabbits[2].
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