BF389
CAS No. : 127245-22-1
(Synonyms: Biofor 389)
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|---|---|---|
| 1mg | $358 | Get quote |
| 5mg | $894 | Get quote |
| 10mg | $1306 | Get quote |
| 50 mg | Get quote | |
| 100 mg | Get quote | |
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| Cat. No. : | HY-106897 |
| M.Wt: | 331.45 |
| Formula: | C20H29NO3 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
BF389 (Biofor 389) is an orally active anti-inflammatory and analesis agent. BF389 is also an inhibitor of cyclooxygenase and 5-lipoxygenase, with IC50s of 4 and 8 ug/mL for COX-1 and COX-2 respectively. BF389 can be used for arthritis research[1][2][3].
In Vitro:BF389 inhibits the production of PGE2 and LTB4 formation with IC50s of 0.84 μM and 3.65 μM respectively[2].
In Vivo:BF389 (1-30 mg/kg, p.o., five daily oral doses) inhibits paw swelling in rats, with an ED50 of 4.9 mg/kg, indicating the anti-inflammatory activity[1].
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