Sulfamerazine (sodium salt)
CAS No. : 127-58-2
(Synonyms: Soluble sulfamerazine)
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| Cat. No. : | HY-B0512A |
| M.Wt: | 286.29 |
| Formula: | C11H11N4NaO2S |
| Purity: | >98 % |
| Solubility: | 10 mM in H2O |
Sulfamerazine Sodium is a sulfonamide antibacterial. Target: Antibacterial Sulfamerazine, the monomethyl derivative of sulfadiazine, is 2-sulfanilamido-4-methylpyrimidine. Sulfamerazine is a sulfonamide drug that inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA) for binding to dihydropteroate synthetase (dihydrofolate synthetase). Sulfamerazine is bacteriostatic in nature. Inhibition of dihydrofolic acid synthesis decreases the synthesis of bacterial nucleotides and DNA [1].
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