| Size | Price | Stock |
|---|---|---|
| 2mg | $105 | In-stock |
| 5mg | $190 | In-stock |
| 10mg | $304 | In-stock |
| 25mg | $578 | In-stock |
| 50mg | $890 | In-stock |
| 100 mg | Get quote | |
| 200 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
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Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-13033 |
| M.Wt: | 363.81 |
| Formula: | C18H19ClFN3O2 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 100 mg/mL |
CDK-IN-2 is a specific CDK9 inhibitor with an IC50 of less than 8 nM. CDK-IN-2 reduces the phosphorylation level of H3S10. CDK-IN-2 decreases the transition rate of spermatocytes from prophase to metaphase I[1][2]. In Vitro:CDK-IN-2 (5.9 μM; 12 h) significantly reduces the proportion of spermatocytes transitioning from prophase to metaphase I in mouse primary spermatocytes (58.3% vs 96.4% in the control group) and reduces the phosphorylation level of the meiotic metaphase marker H3S10[2].
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