(R)-(-)-JQ1 Enantiomer


CAS No. : 1268524-71-5

1268524-71-5
Price and Availability of CAS No. : 1268524-71-5
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10mg $140 In-stock
25mg $240 In-stock
50mg $380 In-stock
100mg $620 In-stock
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Cat. No. : HY-13030A
M.Wt: 456.99
Formula: C23H25ClN4O2S
Purity: >98 %
Solubility: DMSO : ≥ 100 mg/mL
Introduction of 1268524-71-5 :

(R)-(-)-JQ1 Enantiomer is the stereoisomer of (+)-JQ1. (+)-JQ1 potently decreases expression of both BRD4 target genes, whereas (R)-(-)-JQ1 Enantiomer has no effect. IC50 & Target: BET bromodomain[1] In Vitro: (R)-(-)-JQ1 Enantiomer shows no significant interaction with any bromodomain. Besides, (R)-(-)-JQ1 Enantiomer is comparatively inactive in nuclear protein in testis (NUT) midline carcinoma (NMC)[1].

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