| Size | Price | Stock |
|---|---|---|
| 1g | $120 | In-stock |
| 5g | $437 | Get quote |
| 10 g | Get quote | |
| 50 g | Get quote | |
| We match the lowest price on market. | ||
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| Cat. No. : | HY-118065 |
| M.Wt: | 302.20 |
| Formula: | C14H17Cl2NO2 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Fenhexamid, a botryticide, is a sterol biosynthesis inhibitor. Fenhexamid shows fungicide efficient against the plant pathogenic fungus Botryotinia fuckeliana (Botrytis cinerea)[1].
In Vitro: Fenhexamid (0.1-10 μM, 24 h-9 days) is the agonist for ERα with EC50 of 9 μM. Fenhexamid enhances the proliferation and migration of ovarian cancer cell BG-1, promotes the expression of cyclin D1 and cathepsin D[2][3].
Fenhexamid (0.1-10 μM, 4 h) promotes angiogenesis of HUVEC cells and increases the expression of VEGF through activation of PI3K signaling pathway[3].
Fenhexamid (0.1-10 μM, 4 h) promotes the EMT process of ER-positive MCF-7 cells, reducse the expression of E-cadherin and Occludin, and increases the expression of N-cadherin and Vimentin[4].
In Vivo: Fenhexamid (20 mg/kg, ip, every 3 days for 80 days) exhibits no effect on tumor growth in BG-1 xenograft mouse models, but exhibits toxicity in mice[2].
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